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Qiong CHEN, Qing YU, Yuhu SONG, Peiyuan Li, Ying CHANG, Zhijun WANG, Lifeng LIU, Wei WU, Jusheng LIN
《医学前沿(英文)》 2009年 第3卷 第2期 页码 148-152 doi: 10.1007/s11684-009-0032-7
关键词: gene X-linked inhibitor of apoptosis protein associated factor-1 (XAF1) promoter transcription regulation
Hepatitis B virus X protein upregulates tumor necrosis factor-α expression of rat mesangial cell
Hong-Zhu LU MD, Dan LIU BM, Qi-Hong FAN BM, Jian-Hua ZHOU MD,
《医学前沿(英文)》 2010年 第4卷 第1期 页码 106-111 doi: 10.1007/s11684-010-0004-y
关键词: hepatitis B virus X gene glomerular mesangial cell line extracellular regulated protein kinases tumor necrosis factor-α
《医学前沿(英文)》 页码 889-906 doi: 10.1007/s11684-023-0994-x
关键词: primary central nervous system lymphoma whole-genome sequencing TMSB4X copy number variation gene mutation
夏家辉
《中国工程科学》 2000年 第2卷 第11期 页码 1-11
介绍了中国医学遗传学国家重点实验室在遗传病家系收集、疾病基因定位、疾病基因克隆和疾病基因功能研究方面的研究工作。用细胞遗传学G显带技术于1975年发现了一条与鼻咽癌相关的标记染色体t(1;3)(q44;p11);1981年将睾丸决定基因(TDF)定位于Yp11.32带;1991年以来收集遗传病家系345种共590个;1996年用显微切割、PCR、微克隆技术克隆了EXT2基因;1998年用基因家族-候选疾病基因克隆方法克隆了遗传性神经性耳聋基因GJB3;1999年用连锁分析和全基因组扫描将一种遗传性弥漫性浅表性光敏性汗孔角化症定位于12q23.2带,并在基因功能研究中发现了一个新的细胞内转运蛋白。
关键词: 遗传病家系 基因定位和克隆 基因家族-候选疾病基因克隆 基因组扫描 基因功能研究
采用白光X射线源和模拟阵列能量色散阵列探测器的高通量粉末衍射技术 Article
汪晓平, 董伟伟, 张鹏, 唐浩琪, 张澜庭, 杨铁莹, 刘鹏, 汪洪, 项晓东
《工程(英文)》 2022年 第10卷 第3期 页码 81-88 doi: 10.1016/j.eng.2021.05.023
Molecular engineering of dendrimer nanovectors for siRNA delivery and gene silencing
Yu Cao, Xiaoxuan Liu, Ling Peng
《化学科学与工程前沿(英文)》 2017年 第11卷 第4期 页码 663-675 doi: 10.1007/s11705-017-1623-5
关键词: gene therapy RNAi therapeutics dendrimer nanovectors gene silencing
史开泉,陈泽雄
《中国工程科学》 2000年 第2卷 第2期 页码 41-46
利用数据生成技术,提出生成锁P <G ,X, X´>
The antibiotic resistome: gene flow in environments, animals and human beings
null
《医学前沿(英文)》 2017年 第11卷 第2期 页码 161-168 doi: 10.1007/s11684-017-0531-x
The antibiotic resistance is natural in bacteria and predates the human use of antibiotics. Numerous antibiotic resistance genes (ARGs) have been discovered to confer resistance to a wide range of antibiotics. The ARGs in natural environments are highly integrated and tightly regulated in specific bacterial metabolic networks. However, the antibiotic selection pressure conferred by the use of antibiotics in both human medicine and agriculture practice leads to a significant increase of antibiotic resistance and a steady accumulation of ARGs in bacteria. In this review, we summarized, with an emphasis on an ecological point of view, the important research progress regarding the collective ARGs (antibiotic resistome) in bacterial communities of natural environments, human and animals, i.e., in the one health settings. We propose that the resistance gene flow in nature is “from the natural environments” and “to the natural environments”; human and animals, as intermediate recipients and disseminators, contribute greatly to such a resistance gene “circulation.”
Reflections on the system of evaluation of gene-edited livestock
Ziyao FAN, Tianwen WU, Kui WU, Yulian MU, Kui LI
《农业科学与工程前沿(英文)》 2020年 第7卷 第2期 页码 211-217 doi: 10.15302/J-FASE-2019303
The rapid development of biotechnology has provided a greater understanding of the biological functions of major candidate genes that have important functions regarding economic traits, and new materials for livestock breeding have been obtained through gene editing (GE) and embryo manipulation with the purpose of improving quality and output and reducing the costs and risk of disease. Public concerns, particularly over safety risks and production performance, must be addressed. Evaluation is the most important component of the regulation of gene-edited livestock and is a crucial guarantee of public safety before the marketing of gene-edited animal products. Here, the system of evaluation of gene-edited livestock is discussed in terms of public safety and production performance. The search for safe and ethical applications in the GE of livestock, a case-by-case evaluation strategy, and classification and simplification are used in order to promote a more efficient, objective, comprehensive and operable evaluation system.
《医学前沿(英文)》 2022年 第16卷 第4期 页码 627-636 doi: 10.1007/s11684-020-0815-4
关键词: RUNX1 gene mutation acute myeloid leukemia transcriptional repression DNA methylation
A mini review: Shape memory polymers for biomedical applications
Kaojin Wang, Satu Strandman, X. X. Zhu
《化学科学与工程前沿(英文)》 2017年 第11卷 第2期 页码 143-153 doi: 10.1007/s11705-017-1632-4
关键词: shape memory polymer biodegradability biocompatibility biomedical application bile acids
Construction of lentiviral vector carrying Rab9 gene and its expression in mouse brain
Youguo HAO, Min ZHANG, Jinzhi XU, Bitao BU, Jiajun WEI
《医学前沿(英文)》 2009年 第3卷 第2期 页码 141-147 doi: 10.1007/s11684-009-0041-6
A study on quality evaluation for bituminous mixture using X-ray CT
Satoshi TANIGUCHI, Keiichiro OGAWA, Jun OTANI, Itaru NISHIZAKI
《结构与土木工程前沿(英文)》 2013年 第7卷 第2期 页码 89-101 doi: 10.1007/s11709-013-0197-7
关键词: asphalt concrete mixture aggregate bitumen bitumen content quality evaluation X-ray CT
Adsorption of fluoride on clay minerals and their mechanisms using X-ray photoelectron spectroscopy
Junyi DU, Daishe WU, Huayun XIAO, Ping LI
《环境科学与工程前沿(英文)》 2011年 第5卷 第2期 页码 212-226 doi: 10.1007/s11783-010-0255-5
关键词: clay mineral fluoride (F) adsorption mechanism X-ray photoelectron spectroscopy (XPS)
Huaneng XU, Haiying CHEN, Weining HUANG,
《化学科学与工程前沿(英文)》 2009年 第3卷 第4期 页码 383-385 doi: 10.1007/s11705-009-0249-7
关键词: separation technique thermal hysteresis cold-acclimated purification X-114
标题 作者 时间 类型 操作
Cloning of human XAF1 gene promoter and assay of its transcription activity in a variety of cell lines
Qiong CHEN, Qing YU, Yuhu SONG, Peiyuan Li, Ying CHANG, Zhijun WANG, Lifeng LIU, Wei WU, Jusheng LIN
期刊论文
Hepatitis B virus X protein upregulates tumor necrosis factor-α expression of rat mesangial cell
Hong-Zhu LU MD, Dan LIU BM, Qi-Hong FAN BM, Jian-Hua ZHOU MD,
期刊论文
Analysis of the genomic landscape of primary central nervous system lymphoma using whole-genome sequencing in Chinese patients
期刊论文
Molecular engineering of dendrimer nanovectors for siRNA delivery and gene silencing
Yu Cao, Xiaoxuan Liu, Ling Peng
期刊论文
Reflections on the system of evaluation of gene-edited livestock
Ziyao FAN, Tianwen WU, Kui WU, Yulian MU, Kui LI
期刊论文
Distinct gene expression pattern of mutations coordinated by target repression and promoter hypermethylation
期刊论文
A mini review: Shape memory polymers for biomedical applications
Kaojin Wang, Satu Strandman, X. X. Zhu
期刊论文
Construction of lentiviral vector carrying Rab9 gene and its expression in mouse brain
Youguo HAO, Min ZHANG, Jinzhi XU, Bitao BU, Jiajun WEI
期刊论文
A study on quality evaluation for bituminous mixture using X-ray CT
Satoshi TANIGUCHI, Keiichiro OGAWA, Jun OTANI, Itaru NISHIZAKI
期刊论文
Adsorption of fluoride on clay minerals and their mechanisms using X-ray photoelectron spectroscopy
Junyi DU, Daishe WU, Huayun XIAO, Ping LI
期刊论文